Natrual stevia CAS：91722-21-9

Natural Stevia stands as the most commercially significant plant-derived sweetener on the global market today. Extracted from the leaves of Stevia rebaudiana Bertoni, it delivers intense sweetness – up to 300 times sweeter than sucrose – with zero calories and a negligible glycemic index. Furthermore, regulatory authorities in over 60 countries, including the EU, US FDA, and Health Canada, recognize Natural Stevia extract as a safe, approved food additive and dietary supplement ingredient.

Moreover, growing consumer demand for sugar reduction and clean-label formulation drives unprecedented adoption of Natural Stevia across the food and beverage industry. Additionally, its non-cariogenic, diabetic-friendly, and keto-compatible profile makes it a top-priority ingredient for health-conscious product development teams worldwide.

Scientific Reference: Safety and Efficacy of Steviol Glycosides – EFSA Scientific Opinion

 

What Is Natural Stevia – Chemistry, Origin, and Key Compounds

Natural Stevia refers to the purified extract obtained from the dried leaves of Stevia rebaudiana Bertoni, a perennial shrub native to Paraguay and Brazil. Specifically, scientists identify steviol glycosides as the primary sweet-tasting compounds responsible for the plant’s extraordinary sweetness. These glycosides include rebaudioside A (Reb-A), rebaudioside D (Reb-D), rebaudioside M (Reb-M), and stevioside – each differing in sweetness intensity and flavor profile.

Notably, Rebaudioside A dominates commercial Natural Stevia extracts due to its superior sweetness clarity and minimal bitter aftertaste. In addition, next-generation Reb-D and Reb-M offer an even cleaner, sugar-like taste experience. Consequently, formulators increasingly select these premium-grade steviol glycosides for applications where taste quality is paramount.

 

Botanical Source & Cultivation of Our Natural Stevia Raw Material

Stevia Rebaudiana – The Sweet Leaf Plant Behind Natural Stevia

Our Natural Stevia originates exclusively from Stevia rebaudiana Bertoni – a member of the Asteraceae (daisy) family. The plant thrives in subtropical and temperate climates with well-drained, slightly acidic soils. Furthermore, our cultivation partners operate dedicated Stevia rebaudiana plantations in Fujian and Yunnan Provinces, China – regions recognized globally for producing high-stevioside-content stevia leaf with consistent quality across seasons.

Sustainable Farming Practices for Premium Natural Stevia Quality

Moreover, our farming partners apply integrated pest management (IPM) protocols and eliminate synthetic pesticide use throughout the growing cycle. They harvest Stevia rebaudiana leaves at peak glycoside accumulation – typically just before the first flowering stage. At this point, steviol glycoside concentrations reach their maximum, delivering raw material that consistently yields high-potency Natural Stevia extract with optimal purity after downstream processing.

 

Steviol Glycoside Content & Standardization Grades of Our Natural Stevia

Our Natural Stevia portfolio covers a full range of steviol glycoside purity levels, allowing formulators to match ingredient cost, sweetness intensity, and taste profile to specific product requirements. Additionally, we offer customized ratio blends on request to meet proprietary formulation specifications.

• Steviol Glycosides ≥ 80% (Total): Standard-grade Natural Stevia for general food and beverage cost-effective sweetening applications.
• Rebaudioside A ≥ 95% (Reb-A 95): Premium Natural Stevia grade with clean taste profile; most widely adopted commercial grade.
• Rebaudioside A ≥ 97–99% (Reb-A 97 / 99): Ultra-pure Natural Stevia for premium low-calorie beverage, dairy, and confectionery products.
• Rebaudioside D ≥ 90% (Reb-D 90): High-value Natural Stevia grade delivering superior sugar-like taste with virtually no aftertaste.
• Rebaudioside M ≥ 90% (Reb-M 90): Next-generation Natural Stevia with the most authentic sucrose-mirroring sensory profile.
• Enzyme-Modified Stevia (EMS): Natural Stevia processed via enzymatic glycosylation for improved solubility and milder flavor.

Technical Reference: Steviol Glycosides in Foods: Global Regulatory Overview (Comprehensive Reviews in Food Science)

 

Complete Technical Specifications of Natural Stevia Extract Powder

Quality Parameter	Specification (Natural Stevia Extract Powder)
Product Name	Natural Stevia Extract Powder (Steviol Glycosides)
CAS Number	91722-21-9
Botanical Latin Name	Stevia rebaudiana Bertoni
Plant Part Used	Leaf
Extraction Method	Hot water extraction, membrane filtration, resin adsorption, spray drying
Standard Grades	Total glycosides ≥80%; Reb-A ≥95%, ≥97%, ≥99%; Reb-D ≥90%; Reb-M ≥90%; EMS
Sweetness Intensity	200–300× sweeter than sucrose (grade-dependent)
Caloric Value	0 kcal/serving (regulatory approved)
Glycemic Index	0 (no blood glucose impact)
Physical Appearance	Fine free-flowing white to off-white powder
Odor & Taste	Characteristic sweet herbal note; clean finish (Reb-A/D/M grades)
Solubility	Freely soluble in water; soluble in ethanol
pH (1% solution)	4.5 – 7.0
Moisture Content	≤ 5.0%
Mesh Granularity	80 Mesh standard; 100 Mesh available
Heavy Metals	Pb ≤ 1.0 ppm | As ≤ 1.0 ppm | Cd ≤ 1.0 ppm | Hg ≤ 0.1 ppm
Microbial Limits	TPC ≤ 1,000 CFU/g | Yeast & Mold ≤ 100 CFU/g | Salmonella: Neg | E.coli: Neg
Pesticide Residues	EU Regulation 396/2005 compliant; Reb-A grades: non-detectable
Regulatory Status	FDA GRAS; EU-approved (E960); JECFA ADI: 4 mg/kg bw/day
Non-GMO	Certified Non-GMO Project Verified (on request)
Shelf Life	24 months under recommended storage conditions
Storage Conditions	Cool (≤ 25°C), dry, sealed; away from direct light
Packaging Options	1 kg foil bag | 5 kg foil bag | 25 kg fiber drum with PE liner

 

Key Functional Benefits of Natural Stevia for Product Formulation

Natural Stevia Delivers Powerful Calorie Reduction Without Compromising Taste

Natural Stevia enables product developers to cut total caloric content by up to 40% in most formulations. Unlike artificial sweeteners such as aspartame or acesulfame-K, Natural Stevia carries a plant-based clean-label credential that resonates powerfully with today’s health-conscious consumer segment. Furthermore, it remains heat-stable up to 200°C, making it fully compatible with baking, pasteurization, and UHT processing without any sweetness degradation.

Natural Stevia Supports Blood Sugar Management and Diabetic-Friendly Formulation

Beyond calorie reduction, Natural Stevia carries a glycemic index of zero, meaning it produces no measurable increase in blood glucose or insulin levels after consumption. Specifically, multiple clinical studies confirm that steviol glycosides do not interfere with glucose metabolism in healthy and type-2 diabetic subjects alike. As a result, food manufacturers actively select Natural Stevia as the sweetener of choice for diabetic-friendly, keto-aligned, and low-carb product lines.

Natural Stevia Offers Dental Health Advantages Over Conventional Sugars

Additionally, Natural Stevia demonstrates non-cariogenic properties – meaning oral bacteria cannot ferment steviol glycosides into acid that erodes tooth enamel. This makes Natural Stevia an ideal sweetener for functional confectionery, chewing gum, oral care products, and children’s food items. Consequently, brands targeting dental health positioning now incorporate our Natural Stevia extract as a core ingredient in their sugar-free product platforms.

Natural Stevia Exhibits Antioxidant and Metabolic Support Properties

Moreover, emerging scientific evidence reveals that Natural Stevia compounds exert antioxidant activity by scavenging reactive oxygen species (ROS). Researchers also document potential blood pressure-moderating effects of stevioside at higher intake levels. Therefore, supplement brands and functional food developers increasingly incorporate Natural Stevia not only as a sweetener, but also as a bioactive ingredient contributing to metabolic wellness positioning in their formulations.

Clinical Research: Stevia rebaudiana Glycosides and Blood Glucose Control – Meta-Analysis (PubMed)

 

Target Industries & Formulation Applications for Natural Stevia Extract

Our bulk Natural Stevia powder serves a broad spectrum of finished product categories across global manufacturing sectors:

Food & Beverage Manufacturing: Soft drinks, flavored water, fruit juices, RTD teas, yogurt, ice cream, jams, sauces, baked goods, and confectionery items all benefit from Natural Stevia as a zero-calorie sweetening solution.

Dietary Supplements: Protein powders, meal replacement shakes, vitamin gummies, pre-workout blends, and fiber supplements rely on Natural Stevia for pleasant taste without caloric penalty.

Nutraceuticals & Functional Foods: Weight management products, blood sugar support formulas, gut health drinks, and immunity-boosting shots incorporate Natural Stevia as a clean-label sweetener and bioactive contributor.

Dairy & Plant-Based Alternatives: Sweetened plant-based milks, protein yogurts, kefir drinks, and cheese-flavored spreads use Natural Stevia to achieve reduced-sugar claims without sacrificing consumer taste acceptance.

Confectionery & Oral Care: Sugar-free chewing gum, hard candy, lozenges, toothpaste, and mouthwash products leverage the non-cariogenic profile of Natural Stevia to support tooth-friendly positioning.

Sports Nutrition: Energy gels, electrolyte drinks, BCAA beverages, and recovery formulas choose Natural Stevia for clean sweetness that aligns with athlete clean-label and keto-friendly dietary preferences.

Cross-sell opportunities (internal links): Monk Fruit Extract [/products/monk-fruit-extract] | Erythritol [/products/erythritol] | Inulin Powder [/products/inulin-powder]

 

Rigorous Quality Control & Global Certifications for Natural Stevia

Botanical Identity Verification Ensures Authentic Natural Stevia Quality

Our quality control team verifies the botanical authenticity of every incoming Stevia rebaudiana leaf batch before extraction begins. First, our botanists conduct macroscopic and microscopic leaf identification. Next, they apply HPTLC fingerprint analysis against certified reference standards. Additionally, we perform steviol glycoside profiling via HPLC-UV to confirm the correct compound ratios and eliminate risk from adulteration or species substitution.

Multi-Stage In-Process Testing Guarantees Natural Stevia Potency Consistency

Throughout the extraction and purification workflow, our QC team runs continuous in-line HPLC monitoring at leaf extraction, resin adsorption, and spray-drying stages. This real-time approach catches any potency drift before it reaches the finished batch. Beyond glycoside content, we test all Natural Stevia intermediates for pesticide residues, heavy metals, and microbial contamination at multiple critical control points – not only upon final product release.

Complete Release Documentation Supports Regulatory Compliance Worldwide

Before we ship any Natural Stevia order, our team completes a full release testing panel: HPLC potency assay, microbial screen (TPC, yeast, mold, Salmonella, E. coli), heavy metal analysis by ICP-MS, pesticide screen, and physical characterization. Furthermore, every shipment includes a complete documentation package: COA, MSDS/SDS, heavy metal certificate, pesticide residue report, non-GMO statement, Halal/Kosher certificate, and allergen declaration. Consequently, our customers successfully pass EU, US, Canadian, Australian, and ASEAN regulatory audits with full confidence.

 

Certifications & Regulatory Compliance for Our Natural Stevia Supply Chain

FDA GRAS Recognized: Natural Stevia (Reb-A) holds FDA GRAS status under 21 CFR, allowing direct US market access.

EU E960 Approved: Our Natural Stevia meets EU food additive standard E960 for broad European market use.

ISO 9001:2015: Quality Management System covers all Natural Stevia production and documentation processes.

ISO 22000 / FSSC 22000: Food safety management system certification for all Natural Stevia processing lines.

HALAL Certified: Our Natural Stevia meets global Muslim market dietary requirements.

KOSHER Certified: Our Natural Stevia complies with Jewish dietary law standards.

Non-GMO Project Verified: Natural Stevia verified free from genetically modified organisms (on request).

GMP Manufacturing: All Natural Stevia production runs under pharmaceutical-grade GMP conditions.

Frequently Asked Questions About Natural Stevia Extract

Q: What is the CAS number for Natural Stevia?

A: The CAS number for Natural Stevia (steviol glycosides) is 91722-21-9. This number specifically identifies the mixture of steviol glycosides standardized from Stevia rebaudiana leaf extract.

 

Q: How sweet is Natural Stevia compared to sugar?

A: Natural Stevia extract is approximately 200–300 times sweeter than sucrose, depending on the steviol glycoside grade. Specifically, Reb-A 95 delivers around 250–300× sweetness intensity, while Reb-M offers an even cleaner, more sugar-like sweetness at similar potency.

 

Q: Does Natural Stevia affect blood sugar levels?

A: Natural Stevia carries a glycemic index of zero and produces no measurable blood glucose response. Multiple clinical trials confirm this property in both healthy and diabetic subjects. Consequently, food manufacturers widely choose it for diabetic-friendly and keto product positioning.

 

Q: Is your Natural Stevia suitable for hot food processing?

A: Yes. Our Natural Stevia extract remains fully heat-stable up to 200°C. Furthermore, it maintains sweetness consistency throughout baking, pasteurization, and UHT treatment, making it ideal for a broad range of hot-process manufacturing applications.

 

Q: What is the minimum order quantity for Natural Stevia?

A: We accommodate orders from 100 g research samples up to full container-load commercial volumes. Additionally, we maintain ready stock of our highest-demand grades – Reb-A 95, Reb-A 97, and Total Glycosides 80% – for rapid dispatch within 5–7 business days of order confirmation.