Black Cohosh Extract CAS :84776-26-1

-Plant extracts

1.Black Cohosh Extract CAS 84776-26-1

2.Cimicifuga Racemosa Root Powder

3.Triterpene Glycosides Standardized Extract

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Product information

Black Cohosh Extract — Premium Actaea racemosa Root Extract

Standardized Botanical Extract for Women’s Health, Menopause Support, and Herbal Supplement Formulations

 

Product Overview

Black Cohosh Extract (Actaea racemosa, formerly Cimicifuga racemosa) stands as one of the most clinically studied herbal ingredients for women’s health applications worldwide. Specifically, triterpene glycosides — actein, 23-epi-26-deoxyactein, and cimicifugoside — serve as the primary bioactive markers that modulate serotonin receptors and support hormonal balance during menopause. Furthermore, the European Medicines Agency (EMA) and the German Commission E have formally recognized Black Cohosh for vasomotor symptom relief, including hot flashes, night sweats, and mood fluctuations. Additionally, our extract uses mature rhizome and root material from sustainably harvested North American plants, ensuring optimal triterpene glycoside concentrations in every batch.

Moreover, our proprietary extraction process combines hydroalcoholic percolation with low-temperature concentration to preserve heat-sensitive actein isomers that conventional drying methods often degrade. Consequently, formulators across dietary supplement, functional food, and herbal medicine industries rely on our standardized Black Cohosh Extract for consistent potency, excellent flowability, and full regulatory documentation that simplifies EU Novel Food and US FDA NDI regulatory submissions.

Key Specifications

Parameter Specification
Product Name Black Cohosh Extract
Botanical Source Actaea racemosa L. (syn. Cimicifuga racemosa) — dried root and rhizome
CAS Number 84776-26-1
Active Markers Triterpene glycosides (HPLC): actein, 23-epi-26-deoxyactein, cimicifugoside
Standardization 2.5%–10% triterpene glycosides (customizable)
Available Forms Fine powder, granulated powder, liquid extract, capsules, bulk packaging
Appearance Light tan to brownish-yellow fine powder
Particle Size 95% pass 80 mesh
Solubility Partially soluble in water; fully soluble in ethanol
Moisture ≤ 5.0%
Heavy Metals Pb ≤ 1.0 mg/kg, As ≤ 0.5 mg/kg, Hg ≤ 0.1 mg/kg, Cd ≤ 0.3 mg/kg
Microbiology TPC ≤ 1,000 cfu/g; E. coli & Salmonella absent
Pesticides Complies with USP Chapter 561 and EU Regulation 396/2005
Shelf Life 24 months stored cool, dry, away from light
Packaging 1 / 5 / 25 kg food-grade sealed bags or fiber drums with inner liner
Origin China — Shaanxi Baisfu Bio-Engineering (sourced from certified plantations)

 

Health Benefits & Applications

Black Cohosh extract exerts its physiological effects through serotonin receptor modulation (5-HT1A, 5-HT7), dopaminergic pathway interaction, and anti-inflammatory cytokine regulation. Specifically, triterpene glycosides act as selective estrogen receptor modulators (SERMs) without binding directly to estrogen receptors, creating therapeutic benefits that avoid hormone-dependent risks.

 

Menopause Support & Women’s Health Supplements

Dietary supplement brands formulate Black Cohosh Extract into tablets, capsules, and liquid tinctures targeting perimenopausal and menopausal symptom relief. Furthermore, randomized controlled trials consistently report statistically significant reductions in hot flash frequency and severity compared to placebo. Additionally, combination formulations pairing Black Cohosh with Dong Quai, Chasteberry, or Soy Isoflavones create comprehensive women’s health stacks that capture multiple consumer search intents on Amazon and Google.

 

Bone Health & Osteoporosis Prevention

Emerging research links Black Cohosh triterpene glycosides to osteoblast differentiation and reduced bone resorption markers. Consequently, bone-health supplement brands incorporate this extract alongside calcium, vitamin D3, and vitamin K2 to create evidence-backed formulations for postmenopausal bone density support. Moreover, the plant-based origin appeals strongly to consumers seeking non-hormonal alternatives to conventional bone-loss therapies.

 

Mood Support & Neurological Wellness

Formulators in the nootropic and stress-management categories increasingly value Black Cohosh for its serotonergic activity. Specifically, the extract’s interaction with 5-HT receptors supports balanced mood, reduced anxiety perception, and improved sleep quality during hormonal transition periods. Furthermore, brands combine it with Ashwagandha, Lemon Balm, and Magnesium in advanced stress-relief complexes.

 

Anti-Inflammatory & Joint Health Formulations

Beyond women’s health, Black Cohosh finds application in joint-support supplements due to its cycloartane-type triterpenoid content, which demonstrates COX-2 inhibitory activity. Additionally, formulators pair it with Turmeric, Boswellia, and MSM in comprehensive mobility-support stacks targeting active aging consumers.

 

Why Choose Baisfu – Shaanxi Baisfu Bio-Engineering

Shaanxi Baisfu Bio-Engineering Co., Ltd. delivers premium botanical extracts to over 50 countries with manufacturing excellence spanning more than 15 years. Furthermore, our vertically controlled supply chain for Black Cohosh begins with authenticated Actaea racemosa root material sourced from certified cultivation partners, verified through botanical DNA barcoding and macroscopic organoleptic screening before extraction. Additionally, our GMP-compliant facility operates under ISO 9001, ISO 14001, KOSHER, HALAL, and Eurofins quality systems, providing clients with comprehensive regulatory confidence for every shipment.

Moreover, our R&D team continuously optimizes extraction conditions to maximize triterpene glycoside recovery while minimizing residual solvent levels and ensuring microbial stability throughout the 24-month shelf life. Consequently, clients receive thoroughly documented extract batches that exceed USP monograph and European Pharmacopoeia requirements. Furthermore, our multilingual commercial team ensures responsive communication in English, Spanish, French, and Arabic — from initial sample request through full container delivery.

  • Consistent triterpene glycoside profile verified by independent HPLC analysis per batch
  • Flexible standardization from 2.5% to 10% triterpene glycosides
  • DNA-authenticated botanical identity with certificate of plant origin
  • Free evaluation samples (30–50 g) for qualified buyers
  • Short lead time: 5–10 business days for standard grades
  • Complete documentation: COA, MSDS, TDS, GMO-Free, allergen statement, certificate of origin
  • OEM / private label services available for capsules, tablets, and finished formats
  • Experienced in EU Novel Food, US FDA NDI, and TGA Australia compliance documentation

Quality Assurance & Analytical Testing

Every production batch undergoes rigorous multi-stage quality control at our in-house analytical laboratory. Specifically, HPLC-DAD quantifies individual triterpene glycosides including actein and 23-epi-26-deoxyactein as primary marker compounds. Furthermore, GC-MS screens for pesticide residues exceeding USP and EU MRL thresholds, while ICP-MS verifies heavy metal compliance. Additionally, we conduct accelerated stability testing at 40℃ / 75% RH to confirm shelf-life claims, and we retain reference samples from every lot for 36 months to support full traceability and retrospective quality investigations.

Ordering & Delivery

We welcome both R&D sample requests and commercial-scale purchase orders. Typically, our sales team responds within 4 business hours with a detailed quotation, COA specimen, and confirmed delivery timeline. Furthermore, qualified buyers receive complimentary evaluation samples (30–50 g) to assess quality, solubility, and formulation compatibility before committing to larger volumes.

Item Details
Sample Policy 30–50 g free sample, freight collect
MOQ 1 kg standard; smaller R&D quantities available
Lead Time 5–10 days for stocked specs; 15–20 days for custom concentrations
Shipping Terms EXW, FOB, CIF per buyer preference
Payment Terms T/T, L/C, PayPal for sample orders
Storage Cool (< 25℃), dry, protect from light; reseal tightly after opening