Lumbrokinase powder CAS :556743-18-1

-Plant extracts

1.Thrombolysis
2.Blood circulation improvement
3.Cardiovascular support

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Product information

Product Overview

Lumbrokinase Powder represents a highly purified fibrinolytic enzyme complex that manufacturers extract directly from fresh earthworms (Lumbricus rubellus / Eisenia fetida) through an advanced enzymatic hydrolysis process. Our production facility in China employs proprietary extraction and purification technologies to deliver a consistent, single-source enzyme ingredient — free from any blending with nattokinase or other mixed fibrinolytic systems. Moreover, we maintain complete control over the entire supply chain, from our own earthworm farming base through to final freeze-drying and packaging. As a result, every batch delivers reliable potency, purity, and traceability that formulators can depend on.

Key Features & Technical Specifications

Appearance Light yellow to brown fine powder with a characteristic odor
CAS Number 556743-18-1
Enzyme Activity 10,000 IU/mg to 50,000 IU/mg (higher activities available upon request)
Assay Method Fibrin plate method — the industry-standard reference for fibrinolytic activity
pH 6.0 – 8.0
Moisture Content ≤ 8%
Ash Content ≤ 9%
Heavy Metals Fully compliant with international pharmacopoeia limits
Source Material 100% pure earthworm extract — single-origin, non-blended enzyme
Production Process Enzymatic hydrolysis followed by freeze-drying, milling, and precision sieving
Shelf Life 24 months under recommended storage conditions
Storage Store in a cool, dry place; keep sealed after opening; avoid repeated temperature fluctuations

Why Our Extraction Process Matters

We operate a self-contained production system that begins at our own earthworm cultivation base. Freshly harvested earthworms pass through a rigorous multi-stage workflow: sorting, washing, freezing, thawing, re-washing, grinding into slurry, and finally undergoing controlled enzymatic hydrolysis. After filtration, the extract enters our freeze-drying chamber, where low-temperature dehydration preserves the delicate enzyme activity. The resulting cake then goes through precision milling and sieving to achieve a uniform particle size. Throughout this entire chain, our in-house quality team monitors critical parameters at every stage.

Because we own the whole process, we eliminate the batch-to-batch variability that often plagues third-party sourced ingredients. In doing so, we offer our customers a level of supply certainty and product consistency that supports long-term formulation stability.

Application Areas

Formulators around the world incorporate Lumbrokinase Powder into a diverse range of finished products. The enzyme’s fibrinolytic properties make it a valuable addition to cardiovascular support supplements, where it targets fibrin buildup and supports healthy blood flow and microcirculation. Beyond that, manufacturers use it in enzyme complex formulations, functional nutrition products, sports recovery blends, and specialized research and development projects exploring fibrinolytic applications.

  • Dietary supplement capsules and tablets targeting cardiovascular wellness
  • Multi-enzyme formulations for systemic fibrin management
  • Functional food and beverage fortification (subject to regional regulations)
  • Sports nutrition and post-exercise recovery products
  • R&D-grade material for enzymatic research and product innovation

Quality Assurance & Compliance

Quality stands at the center of everything we do. Our manufacturing facility operates under strict quality management protocols, and we provide comprehensive documentation with every shipment — including a Certificate of Analysis (COA), detailed specification sheet, product information file, and batch-specific test data. Consequently, our customers gain full visibility into the quality parameters of the material they receive.

Microbiological testing confirms compliance across key indicators:

Total Aerobic Microbial Count < 10 CFU/g
Mold & Yeast < 10 CFU/g
Coliforms < 0.3 MPN/g
Staphylococcus aureus Not Detected
Salmonella Not Detected

Packaging & Logistics

We package Lumbrokinase Powder in food-grade aluminum foil bags at 1.5 kg per bag, with 6 bags per carton (9 kg per carton). In addition, we offer fiber drum packaging and custom packaging solutions to meet specific customer requirements. For international buyers, we ship via DHL or air freight, with typical delivery times of 7 to 15 business days after payment confirmation. Furthermore, we provide DDP (Delivered Duty Paid) shipping to select countries and regions, which simplifies the import process for our customers. The minimum order quantity starts at just 1.5 kg, and we gladly supply 100 g free samples for evaluation purposes.

A Note on Enzyme Activity Measurement

We consider it important to highlight that fibrinolytic enzyme activity can appear under different unit systems across the industry — including IU/mg, FU/g, and LKU. Because each system uses distinct assay methods, substrates, incubation conditions, and calculation formulas, these values do not translate directly from one system to another. Therefore, when you compare activity levels between different suppliers, we strongly recommend that you first confirm the specific assay method and testing standard that each party uses. Our team always provides full transparency regarding our fibrin plate methodology and stands ready to discuss technical details with your quality assurance and R&D teams.

Why Choose Our Lumbrokinase Powder

  • Single-origin purity — you receive 100% earthworm-derived enzyme, never blended with other fibrinolytics
  • Fully integrated supply chain — from our own breeding base through to finished product packaging
  • Outstanding batch consistency — internal process control eliminates third-party variability
  • Flexible activity grades — we tailor the potency to your formulation requirements
  • Comprehensive documentation — COA, spec sheet, and batch data accompany every order
  • Global shipping expertise — DDP options and fast air freight keep your supply chain moving

Get in Touch

We welcome inquiries from dietary supplement manufacturers, contract formulators, and ingredient distributors worldwide. To request a free sample, discuss your specific activity requirements, or receive a tailored quotation, please reach out to our international sales team. Our technical staff will respond promptly with the information and documentation you need to evaluate our Lumbrokinase Powder for your next formulation project.