Andrographolide
-Plant extracts
Product information

Name | Baisfu Andrographolide |
CAS | 5508-58-7 |
Molecular formula | C20H30O5 |
Molecular weight | 350.45 |
EINECS NO. | 226-852-5 |
Melting point | 229-232 °C (lit.) |
Boiling point | 557.3±50.0 °C(Predicted) |
Specific rotation | -126 º (c=1.5,HAc) |
Storage condition | Inert atmosphere,2-8°C |
Solubility | Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 8 mg/ml). |
Acidity coefficient (pKa) | 12.36±0.20(Predicted) |
Color | Off-white |
Form | White like solid |
BRN | 42762 |
Stability | Can be stored in DMSO or ethanol solution at -20°C for up to 3 months. |
Description:
A diterpenoid lactone compound extracted from Andrographolide, which is one of the main active components of Chinese medicine.
It is white square prism or flake crystal in appearance, odorless and bitter in taste.
It dissolve in boiling ethanol, slightly soluble in methanol or ethanol, very slightly soluble in chloroform.
And almost insoluble in water or ether.
It has the effect of dispelling heat and detoxifying, anti-inflammatory and analgesic.
And it has special effect on bacterial and viral upper respiratory tract infection and dysentery, which known as natural antibiotic drugs.
Apply
The main active components of Andrographis paniculata are diterpene lactones, which have anti-inflammatory, antibacterial and antiviral effects.
Among them, the contents of it and dehydrated item are the highest, which one of the strongest compounds in andrographolide.
Drugs made from andrographolide or dehydroandrographolide and its derivatives, such as andrographolide tablets.
Chuanhuning injection, Yanhuning injection, etc., have been widely used in clinic.
Chemical property
White square or rectangular crystal. Melting point 224-230℃ (decomposition).
Soluble in boiling ethanol, slightly soluble in methanol or ethanol, very slightly soluble in chloroform, insoluble in water or ether.
Odorless, extremely bitter taste.
Use
First, antibacterial, anti-inflammatory, heat clearing, antidote.
It suitable for the treatment of bacillary dysentery, acute gastroenteritis, mumps, tonsillitis, pharyngitis.
Upper respiratory tract infection and other diseases.
Andrographolide has the effect of dispelling heat and detoxifying, reducing inflammation and relieving pain.
And has special effect on bacterial and viral upper respiratory tract infection and dysentery, so it known as a natural antibiotic.