Galanthamine CAS: 357-70-0

Galanthamine

Product Name	Galanthamine
Place of Origin	Shaanxi,China
Purity	≥98%
Appearance	White to off-white crystalline powder
Shape	Powder
Category	Plant Extracts
MOQ	5 kg
Shelf Life	24 Months

Detailed Description

Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer’s disease and various other memory impairments, particularly those of vascular origin. It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus Caucasicus (Caucasian snowdrop, Voronov’s snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil)), Leucojum(snowflake) and Lycoris including Lycoris radiata (Red Spider Lily).
Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform,ether and alcohol .

Applications

1.Galanthamine Hydrobromide is mainly used in myasthenia gravis, poliovirus quiescent stage and sequela, also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism.
2.Galanthamine Hydrobromide is also used in Alzheimer’s disease, has the principal function for dement and dysmnesia caused by organic brain damage.

Functions

(1) Anti-cholinesterase .
(2) Stimulate and inhibit acetylcholinesterase, regulate intracephalic nicotine receptor position.
(3) Cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.
(4)Improve the recognition function of light, mild Alzheimer disease patients significantly, and delay the process of function decrease of brain cells.
(5) Improve the conduction between nerve and muscle