Vitexin Extract — Premium Hawthorn-Derived Flavonoid

High-Purity Flavonoid Ingredient for Cardioprotective Supplements, Anti-Diabetic Formulations, and Functional Nutrition

 

Product Overview

Vitexin, an apigenin flavone glucoside, earns growing recognition in nutraceutical science for its broad-spectrum pharmacological profile. Specifically, researchers have identified potent antioxidant, cardioprotective, anti-diabetic, anti-inflammatory, and neuroprotective activities across dozens of preclinical and clinical studies. Furthermore, vitexin occurs naturally in hawthorn leaves (Crataegus spp.), passion flower, bamboo leaves, and mung beans — but hawthorn offers the most concentrated and commercially viable source for standardized extraction. Additionally, our extract uses premium Crataegus pinnatifida leaves harvested from China’s northern orchards, delivering consistent vitexin and total flavonoid content that meets global supplement brand specifications.

Moreover, vitexin distinguishes itself from other flavonoids through its unique ability to cross the blood-brain barrier, enabling direct neuroprotective effects alongside peripheral metabolic benefits. Consequently, formulators increasingly select vitexin-enriched extracts for advanced cardiovascular health, blood sugar management, and cognitive wellness supplement lines that demand scientifically differentiated ingredients beyond generic antioxidants.

Key Specifications

Parameter	Specification
Product Name	Vitexin Extract
Botanical Source	Crataegus pinnatifida Bunge — dried hawthorn leaves
Active Compound	Vitexin (apigenin-8-C-glucoside) + Isovitexin
Vitexin Content	2%–10% (HPLC, customizable)
Total Flavonoids	10%–40% (UV spectrophotometry)
Available Forms	Fine powder, granulated powder, capsules, bulk packaging
Appearance	Light yellow to yellowish-green fine powder
Particle Size	95% pass 80 mesh
Solubility	Soluble in ethanol and methanol; partially soluble in hot water
Moisture	≤ 5.0%
Heavy Metals	Pb ≤ 1.0 mg/kg, As ≤ 0.5 mg/kg, Hg ≤ 0.1 mg/kg, Cd ≤ 0.3 mg/kg
Microbiology	TPC ≤ 1,000 cfu/g; E. coli & Salmonella absent
Shelf Life	24 months under recommended storage
Packaging	1 / 5 / 25 kg food-grade sealed bags or fiber drums
Origin	China — Shaanxi Baisfu Bio-Engineering

 

Health Benefits & Applications

Vitexin exerts its therapeutic effects through multiple molecular targets, including AMPK activation, Nrf2/ARE antioxidant pathway upregulation, NF-kB inflammatory cascade suppression, and GABA receptor modulation. Specifically, these mechanisms create scientifically substantiated applications across cardiovascular, metabolic, neurological, and anti-aging product categories.

 

Cardiovascular Health & Heart Support Supplements

Supplement brands formulate vitexin extract into capsules, tablets, and powdered drink mixes targeting blood pressure regulation, myocardial protection, and endothelial function. Furthermore, research links vitexin to reduced ischemia-reperfusion injury and improved coronary flow in preclinical models. Additionally, its synergy with hawthorn’s other flavonoids — hyperoside and rutin — creates a comprehensive cardioprotective matrix that clinical trials associate with improved exercise tolerance in mild heart failure patients.

 

Blood Sugar Management & Anti-Diabetic Formulations

Vitexin demonstrates significant alpha-glucosidase inhibitory activity and AMPK-mediated glucose uptake enhancement, making it a compelling ingredient for blood sugar support supplements. Moreover, its antioxidant action helps mitigate diabetic complications including nephropathy and neuropathy. Consequently, formulators combine vitexin with berberine, chromium, and cinnamon extract in advanced glycemic control stacks for the rapidly growing metabolic health market.

 

Cognitive Wellness & Neuroprotection

Unlike many flavonoids, vitexin readily crosses the blood-brain barrier and accumulates in brain tissue, where it inhibits acetylcholinesterase, reduces amyloid-beta aggregation, and upregulates BDNF expression. Furthermore, its anxiolytic effects via GABA-A receptor modulation create opportunities for stress-relief and sleep-support formulations. Additionally, nootropic brands increasingly feature vitexin alongside Bacopa monnieri, Lion’s Mane, and Phosphatidylserine in comprehensive brain health stacks.

 

Anti-Aging & Antioxidant Skincare

Cosmetic formulators incorporate vitexin for its potent UV-protective, collagen-preserving, and tyrosinase-inhibiting properties. Specifically, vitexin demonstrates stronger DPPH radical scavenging than vitamin C in several assays. Furthermore, its anti-glycation activity helps prevent advanced glycation end-products (AGEs) that accelerate visible skin aging, creating a differentiated anti-aging ingredient story for premium skincare brands.

 

Why Choose Baisfu – Shaanxi Baisfu Bio-Engineering

Shaanxi Baisfu Bio-Engineering Co., Ltd. brings over 15 years of botanical extraction expertise to the vitexin market, serving clients across more than 50 countries. Furthermore, our vertically integrated supply chain begins with traceable Crataegus pinnatifida leaf material from certified cultivation bases in northern China, verified through macroscopic authentication and HPLC fingerprinting before extraction. Additionally, our GMP-compliant facility operates under ISO 9001, ISO 14001, KOSHER, HALAL, and Eurofins quality management systems, providing complete regulatory confidence for every international shipment.

Moreover, our R&D laboratory has developed proprietary extraction and enrichment protocols that maximize vitexin recovery while minimizing chlorophyll, waxes, and other co-extracted impurities. Consequently, clients receive high-purity vitexin powders with excellent flowability, solubility, and stability profiles that simplify downstream formulation and regulatory compliance. Furthermore, our multilingual account team provides responsive support in English, Spanish, French, and Arabic throughout the entire ordering, logistics, and after-sales process.

• Stable vitexin content verified by independent HPLC analysis per batch
• Flexible standardization: 2% to 10% vitexin, 10% to 40% total flavonoids
• Traceable botanical origin with DNA-authenticated Crataegus species confirmation
• Free evaluation samples (30–50 g) for qualified buyers
• Short lead time: 5–10 business days for standard specifications
• Complete documentation suite: COA, MSDS, TDS, GMO-Free, certificate of origin
• OEM / private label services available for capsules, sachets, and finished dosage forms
• Global logistics experience with EU, US FDA, TGA, and ASEAN customs clearance

Quality Assurance & Testing

Every production batch undergoes comprehensive quality control at our in-house laboratory before release. Specifically, HPLC-DAD quantifies vitexin and isovitexin as primary marker compounds, while UV spectrophotometry confirms total flavonoid content. Furthermore, GC-MS screens for pesticide residues against USP and EU MRL limits, and ICP-MS verifies heavy metal compliance. Additionally, we perform accelerated stability testing at 40℃ / 75% RH and retain reference samples from every production lot for 36 months, ensuring complete traceability from raw material to finished extract.

Ordering & Delivery

We welcome both R&D sample requests and full-scale commercial purchase orders. Typically, our sales team responds within 4 business hours with a comprehensive quotation, COA specimen, and confirmed delivery timeline. Furthermore, qualified buyers receive complimentary evaluation samples (30–50 g) to assess quality, solubility, and formulation compatibility before placing larger orders.

Item	Details
Sample Policy	30–50 g free sample, freight collect
MOQ	1 kg standard; smaller R&D quantities available
Lead Time	5–10 days for stocked specs; 15–20 days for custom concentrations
Shipping Terms	EXW, FOB, CIF per buyer preference
Payment Terms	T/T, L/C, PayPal for sample orders
Storage	Cool (< 25℃), dry, away from light; reseal tightly after opening